Sicily, the largest island in the Mediterranean, on the southern tip of Italy, is a rugged and attractive island and is one of the country's 20 regions. It has a rich and unique culture, especially with regard to the arts, music, literature, cuisine, and architecture. It is also home to the important archaeological and ancient sites, such as the Necropolis of Pantalica, the Valley of the Temples, and Selinunte.      

Florence is the capital city of the Italian region of Tuscany and of the province of Florence. It is the most populous city in Tuscany, with 367,569 inhabitants (1,500,000 in the metropolitan area). The city lies on the River Arno and is known for its history and its importance in the Middle Ages and in the Renaissance, especially for its art and architecture. A centre of medieval European trade and finance and one of the wealthiest cities of the time, Florence is considered the birthplace of the Renaissance; it has been called the Athens of the Middle Ages. Florence is often known as the ''Jewel of the Renaissance''. 

Milan is a city in Italy and the capital of the region of Lombardy and of the province of Milan. The city proper has a population of about 1,315,000, while the urban area is the largest in Italy and the fifth largest in the European Union with a population of 4,345,000 over an area of 2,370 km2 (915 sq mi). The Milan metropolitan area, by far the largest in Italy, is estimated by the OECD to have a population of 7,400,000. The city is the main industrial, commercial, and financial centre of Italy and a leading global city of fashion and design. Its business district hosts the Borsa Italiana (Italy's main stock exchange) and the headquarters of the largest national banks and companies. Milan's museums, theatres and landmarks (including the Milan Cathedral, the fifth-largest cathedral in the world, and Santa Maria delle Grazie, decorated with Leonardo da Vinci paintings such as The Last Supper, a UNESCO World Heritage Site) attract over 8 million visitors annually.