Messina is a harbor city in northeast Sicily, Italy. It is the capital of the Italian Metropolitan City of Messina, and has close ties with Reggio Calabria. The city's main resources are its seaports (commercial and military shipyards), cruise tourism, commerce, and agriculture (wine production and cultivating lemons, oranges, mandarin oranges, and olives). The city has been a Roman Catholic Archdiocese and Archimandrite seat since 1548 and is home to a locally important international fair. The city has the University of Messina, founded in 1548 by Ignatius of Loyola. Messina has a light rail system, Tranvia di Messina, that was opened on 3 April 2003. This line is 7.7 kilometres (4.8 mi) and links the city's central railway station with the city centre and harbour. The city is home to a significant Greek-speaking minority, rooted in its history and officially recognised.

Sicily, the largest island in the Mediterranean, on the southern tip of Italy, is a rugged and attractive island and is one of the country's 20 regions. It has a rich and unique culture, especially with regard to the arts, music, literature, cuisine, and architecture. It is also home to the important archaeological and ancient sites, such as the Necropolis of Pantalica, the Valley of the Temples, and Selinunte.      

Palermo is a city of Southern Italy, the capital of both the autonomous region of Sicily and the Metropolitan City of Palermo. The city is noted for its history, culture, architecture and gastronomy, playing an important role throughout much of its existence; it is over 2,700 years old.  Founded in 734 BC by the Phoenicians as Ziz ('flower'), Palermo is Sicily's cultural, economic and touristic capital. It is a city rich in history, culture, art, music and food. Numerous tourists are attracted to the city for its good Mediterranean weather, its renowned gastronomy and restaurants, its Romanesque, Gothic and Baroque churches, palaces and buildings, and its nightlife and music. The city is also was one of the largest cities in the Mediterranean and is now among the top tourist destinations in both Italy and Europe. It is the main seat of the UNESCO World Heritage Site of Arab-Norman Palermo and the Cathedral Churches of Cefalù and Monreale. The city is also going through careful redevelopment, preparing to become one of the major cities of the Euro-Mediterranean area. Roman Catholicism is highly important in Palermitano culture. The Patron Saint of Palermo is Santa Rosalia whose Feast Day is celebrated on 15 July. The area attracts significant numbers of tourists each year and is widely known for its colourful fruit, vegetable and fish markets at the heart of Palermo, known as Vucciria, Ballarò and Capo.